A recent Parker domnick hunter webinar discussed the question "Is
Standardization Possible in a Custom Single-use World?". The
webinar looked at how high levels of customization has led to...
On July 18, 2016
For biomanufacturers, using a structured, analytical approach to
process scale-up will breed confidence and ensure quality.
By adopting robust experimental design, results gleaned
On July 7, 2016
Buffers are used throughout the production of pharmaceuticals and
buffer filtration is essential in protecting downstream
chromatography and ultrafiltration equipment, controlling bioburden
On May 17, 2016
Filtration is commonly used in biopharmaceutical manufacturing in
order to control bioburden within the production process, and the
appropriate use of prefilters can help to optimize filtration
On March 3, 2016
Parker domnick hunter is committed to increasing productivity and
customer satisfaction through application-driven new product
development, and collaboration is a highly effective way in which
On March 3, 2016
Imagine the scenario: an insulin production facility is forced to
shut down, or production ceases, limiting the availability of
insulin to diabetics around the world. It’s a disturbing picture
On February 24, 2016
Selection of the appropriate filter product for a given application
in your bioprocess is critical, as an incorrect decision at the
specification stage may have significant economic, quality...
On October 12, 2015
Sterilizing filtration is now commonplace in pharmaceutical
manufacturing and is used in order to prevent microbial
contamination from negatively impacting drug quality and, more
On September 3, 2015
There is increasing need to manufacture biopharmaceuticals more
efficiently and cost-effectively due to downwards price pressures
caused by trends such as the emergence of the market for
On August 4, 2015
Single-use tangential flow filtration (TFF) technology offers a
range of benefits in ultrafiltration and microfiltration
applications in bioprocessing. While manufacturers have to fit a
On June 15, 2015
According to conventional wisdom within the biopharmaceutical
industry, cassettes are the most suitable tangential flow
filtration (TFF) technology for ultrafiltration applications such
as protein or...
On June 4, 2015
Advances in technology are allowing biomanufacturers to move
to entirely single-use set-ups for tangential flow filtration
and benefit from the many advantages of single-use technology.
On April 23, 2015
Speed to market is critical for biomanufacturers. The faster a
process can be scaled-up, the faster a return on investment on drug
development costs can be realized. With a strong trend towards...
On March 23, 2015
Single-use technology is quickly gaining in popularity around the
world because of the financial and operational benefits over
traditional process methods using stainless steel. So, why
On February 27, 2015
If quality by design (QbD) promises a more efficient manufacturing
process with more consistent product quality and increased safety,
why is there reluctance among the bioprocessing industry...
On January 27, 2015
Mycoplasma may be the smallest class of free-living microorganism,
but the consequences of contamination in a cell batch can be
huge with manufacturers suffering reduced yields and lost...
On December 22, 2014
Bioprocess variation attributed to operator error can be costly,
leading to decreased process efficiency and reduced product
quality. The application of the skill, rule & knowledge (SRK)
On November 27, 2014
When implementing a single-use bioprocessing solution, various
levels of automation are available from completely manual steps,
through semi-automated to completely automated unit operations....
On November 10, 2014
Mycoplasma contamination events, although infrequent, can have an
enormous and immediate negative impact in terms of lost product
batches, in addition to longer-term restrictions upon...
On November 3, 2014
Automating a bioprocess step reduces process variation, increases
productivity, prevents manual errors and frees up operator time, as
well as improving health & safety and working conditions....
On October 22, 2014