Biopharmaceutical manufacturers have traditionally implemented bulk
final filtration and bulk dispensing as two separate unit
operations – with multiple operators assigned to carrying them
out....
Posted On 10/15/2020
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As well as pharmaceutical production based on complex organic
molecules, manufacturing of advanced biologic drugs and vaccines
must ensure that in-process contamination risks are mitigated...
Posted On 09/21/2020
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Hit and hold circuits enable solenoid valves to be energized to
full power and held for a short duration of time before voltage and
current are reduced significantly to lower levels, while...
Posted On 09/10/2020
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Improving indoor air quality (IAQ) has been a major focus in
manufacturing, industrial, and other commercial environments for
decades, given that poor IAQ can not only cause immediate
deleterious...
Posted On 09/08/2020
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In bulk dispense operations, filtration can sometimes be treated as
either a completely separate unit operation or in some systems as a
bolt-on – an optional module that while performing this
critical...
Posted On 09/03/2020
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Direct acting solenoid valves require a significant amount of
electrical power to change from a normally closed state to an open
or actuated state. Once the valve is fully actuated, the amount...
Posted On 08/28/2020
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There are several technology options in precision measurement
devices but the two that have frequently been compared against
each other are thermal mass flow and differential pressure mass
flow. These...
Posted On 07/30/2020
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Cell culture media is a key component of upstream bioprocessing
needed to encourage the growth and survival of cells. This is vital
to achieving a viable cell density and, ultimately, the...
Posted On 07/28/2020
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Chiller or water cooling systems are used for temperature control
in many applications, from industrial manufacturing to food
and beverage to commercial applications for hospitals and
medical. In many...
Posted On 07/22/2020
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Single-use technology has major benefits for the biopharmaceutical
manufacturing industry. It enables rapid turnaround times between
batches and allows facilities to be multi-product while...
Posted On 07/21/2020
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Developing and introducing a new clinical diagnostic instrument or
medical device is a challenging accomplishment that often takes
years. One of the final steps in bringing life-saving,
life-improving...
Posted On 07/01/2020
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As the benefits of single-use became clear and the technology
became established in the 2000s, there was a drive to utilize it in
more process steps. Single-use was being utilized in steps...
Posted On 06/22/2020
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Human error in bioprocessing can have serious consequences for
biopharmaceutical manufacturers. Accidents can cause a health
hazard for staff involved in bioprocessing operations and human
error can...
Posted On 06/09/2020
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Cooling requirements are widespread in both the industrial and
commercial sectors. Cooling is generally split into two categories:
Process cooling This type of cooling is applied when accurate...
Posted On 06/09/2020
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The high transmission rate of coronavirus (COVID-19) has prompted
the Center for Disease Control and Prevention (CDC) to recommend
that everyone in the U.S. wear nonsurgical face masks when going
out...
Posted On 06/04/2020
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During downstream processing, the value of a product increases with
every unit step of the operation, designed to both remove
impurities and concentrate the biologically active component. Each
of...
Posted On 05/25/2020
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Process chillers for precision cooling of low viscosity
industrial fluids are routinely used in hospitals and laboratories
to control the temperature in a variety of applications including
rotary...
Posted On 05/20/2020
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In the rush to massively increase the number of ventilators
available to treat patients with severe cases of Covid-19, using
the correct seal materials for those ventilators should never take
a back...
Posted On 04/30/2020
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Today, in the midst of the COVID-19 pandemic, keeping
workers, patients and families safe from the spread of disease in
facilities is more important than ever. For facilities managers,
this means...
Posted On 04/29/2020
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A biopharmaceutical customer was reviewing its process for tryptone
soya broth (TSB) and vegetable soya broth (VSB) production.
The existing process incorporated five-step filtration, using...
Posted On 04/08/2020
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