Although bulk filtration of a product prior to shipping was one of
the first bioprocessing steps to benefit from single-use
technology, it has been one of the last to benefit from...
On November 21, 2019
Whether you are running a process in a 30,000 L bioreactor in
fed-batch mode, a 200 L continuous process, or have scaled-out
(rather than up), you will start at small scale and look to
On October 30, 2019
Single-use solutions have been widely adopted on a global scale
within the biopharmaceutical industry due to the many advantages
and process improvements they offer. Key applications for
On October 15, 2019
In the biopharmaceutical industry, extractables and leachables have
come under the spotlight as stainless steel manufacturing systems
have given way to single-use assemblies in...
On October 7, 2019
Parker's Technical Support Group works hand in hand with customers
to help them overcome operational challenges and optimize their
filtration systems. We build close relationships with...
On May 28, 2019
Filter qualification typically involves demonstrating bacterial
retention of a filter under process simulated conditions. A crucial
first step in this is in the hands of the filter vendor, who...
On May 15, 2019
Filter blockages in a beer production process can cause serious
problems for breweries which can include increased expenditure on
replacement filter cartridges and a significant amount of downtime
On May 9, 2019
The consequences of failure during downstream processing are
severe. Following the Affinity Chromatography stage, the value of
the product increases significantly at every step. A failure at the
On January 17, 2019
Mycoplasma contamination events, although rare, can have an
enormous and immediate negative impact on biomanufacturers leading
to reduced productivity and delays in products
reaching patients. Parker...
On January 7, 2019
When it comes to the use of sterile gas for product contact
purposes – such as aseptic packaging or product purge applications
– no clear guidelines have been adopted by the dairy industry
On January 4, 2019
Bacterial contamination in the dairy industry can have major
implications for operators. It can result in product re-work,
wastage or recall – the cost of which can run into millions of
On December 18, 2018
As the brewing industry is becoming more competitive, breweries of
all sizes realize the importance of producing a higher quality
product while keeping an eye on the bottom line at the same time.
On November 20, 2018
The dairy industry is currently enjoying a period of growth,
principally driven by a shift in consumer preference towards
protein-heavy diets as opposed to carbohydrates and an increase in
On September 23, 2018
One of the challenges faced in any biopharmaceutical process is
bioburden control and containment — or how do you keep what is out,
"out" and what is in "in". For a stainless steel-based
On September 13, 2018
The impact of the failure of a sterile air and gas filter can be
potentially catastrophic for operators in the dairy industry. If a
filter has failed, but the problem has not been identified,...
On September 11, 2018
As the craft beer sector continues to grow, mainstream beer sales
continue to decline. Beer production in Europe has been in decline
since the 1970s, and with more and more drinkers demanding a...
On July 17, 2018
Brewers who wish to reach their sustainability goals - and produce
more stable, fresher beer - should consider embracing a technology
which is changing the face of the brewing industry. New...
On July 8, 2018
Any trip to the supermarket will demonstrate just how popular
healthy dairy products are – products which are low in fats, salts,
sugars and preservatives. This trend has driven the growth of
On May 30, 2018
Some of the world’s largest breweries have recently reported a
decline in sales as they have admittedly failed to amend their
brand portfolio to meet consumer trends. Sterile filtration could
On May 16, 2018
Downstream oil and gas operations include refineries and
petrochemical plants where crude oil is processed into finished
products such as jet fuel, diesel, lubricants, and gasoline.
On April 9, 2018