Although bulk filtration of a product prior to shipping was one of the first bioprocessing steps to benefit from single-use technology, it has been one of the last to benefit from...

Whether you are running a process in a 30,000 L bioreactor in fed-batch mode, a 200 L continuous process, or have scaled-out (rather than up), you will start at small scale and look to increase the...

Single-use solutions have been widely adopted on a global scale within the biopharmaceutical industry due to the many advantages and process improvements they offer. Key applications for single-use...

In the biopharmaceutical industry, extractables and leachables have come under the spotlight as stainless steel manufacturing systems have given way to single-use assemblies in...

Parker's Technical Support Group works hand in hand with customers to help them overcome operational challenges and optimize their filtration systems. We build close relationships with...

Filter qualification typically involves demonstrating bacterial retention of a filter under process simulated conditions. A crucial first step in this is in the hands of the filter vendor, who...

Filter blockages in a beer production process can cause serious problems for breweries which can include increased expenditure on replacement filter cartridges and a significant amount of downtime in...

The consequences of failure during downstream processing are severe. Following the Affinity Chromatography stage, the value of the product increases significantly at every step. A failure at the final...

Mycoplasma contamination events, although rare, can have an enormous and immediate negative impact on biomanufacturers leading to reduced productivity and delays in products reaching patients. Parker...

When it comes to the use of sterile gas for product contact purposes – such as aseptic packaging or product purge applications – no clear guidelines have been adopted by the dairy industry regarding...

Bacterial contamination in the dairy industry can have major implications for operators. It can result in product re-work, wastage or recall – the cost of which can run into millions of pounds once...

As the brewing industry is becoming more competitive, breweries of all sizes realize the importance of producing a higher quality product while keeping an eye on the bottom line at the same time. When...

The dairy industry is currently enjoying a period of growth, principally driven by a shift in consumer preference towards protein-heavy diets as opposed to carbohydrates and an increase in the average...

One of the challenges faced in any biopharmaceutical process is bioburden control and containment — or how do you keep what is out, "out" and what is in "in". For a stainless steel-based manufacturing...

The impact of the failure of a sterile air and gas filter can be potentially catastrophic for operators in the dairy industry. If a filter has failed, but the problem has not been identified,...

As the craft beer sector continues to grow, mainstream beer sales continue to decline. Beer production in Europe has been in decline since the 1970s, and with more and more drinkers demanding a...

Brewers who wish to reach their sustainability goals - and produce more stable, fresher beer - should consider embracing a technology which is changing the face of the brewing industry. New...

Any trip to the supermarket will demonstrate just how popular healthy dairy products are – products which are low in fats, salts, sugars and preservatives. This trend has driven the growth of aseptic...

Some of the world’s largest breweries have recently reported a decline in sales as they have admittedly failed to amend their brand portfolio to meet consumer trends. Sterile filtration could be the...

Downstream oil and gas operations include refineries and petrochemical plants where crude oil is processed into finished products such as jet fuel, diesel, lubricants, and gasoline. Refineries operate...